生物 360 邀您共享表观遗传学研究饕餮盛宴 “第四届发育和疾病的表观遗传学上海国际研讨会 ”(2018 年 9 月 18-21 日,上海),点击注册:
http://i.bio360.net/MEET/2018epigenetics/sign.html
表观遗传学 (Epigenetics) 是论及决定细胞时代间基因组 转录记忆 的与 DNA 序列改变无关的信号, 介导者和机制的学科。表观遗传事件通过对 DNA 和组蛋白的 共价修饰 , 以转录的 RNA 和翻译的蛋白的方式, 调节和功能化地展示编码在 DNA 序列中遗传的结构信息, 继而产生在 时空多维空间 无限多样的表型。健康表观遗传稳态是确保高等生物发育过程中细胞分化和谱系化正常开展所依据的优态基因组表达的必要前提。基因组表观遗传信息界面的异常是包括肿瘤, 代谢类和神经系统疾病在内的疾患的病因, 病理学机制之一。
为了加大本次大会学术交流的力度, 除了 6 个主题 /36 个 25 分钟报告以外, 我们还安排了 12 个 10 分钟报告, 后者是从两个时长 1.5 小时的墙报摘要者中遴选出来的。欢迎各位与会者积极报名并提交墙报摘要!
会议主题:
主题 1. DNA 修饰的化学和生物学
主题 2. 组蛋白修饰的化学和生物学
主题 3. 转录的化学生物学和表观调控
主题 4. 临床表观遗传学
主题 5. 染色质高级结构的化学和生物学
主题 6. 发育的表观遗传学
演讲嘉宾:
徐国良(中科院上海生命科学研究院)
http://i.bio360.net/MEET/2018epigenetics/customer.html
朱冰 (中科院生物物理研究所)
http://i.bio360.net/MEET/2018epigenetics/bingzhu.html
James Shen(Academia Sinica,Taipei)
http://i.bio360.net/MEET/2018epigenetics/james.html
伊成器(北京大学)
http://i.bio360.net/MEET/2018epigenetics/chengqi.html
张鹍 (UCSD)
http://i.bio360.net/MEET/2018epigenetics/kunzhang.html
徐彦辉(复旦大学)
http://i.bio360.net/MEET/2018epigenetics/yanhui.html
Naoko Hattori(Japan)
http://i.bio360.net/MEET/2018epigenetics/naoko.html
刘峰 (中科院动物所)
http://i.bio360.net/MEET/2018epigenetics/fengliu.html
陈玲玲 (中科院上海生命科学研究院)
http://i.bio360.net/MEET/2018epigenetics/lingling.html
沈晓骅 (清华大学)
http://i.bio360.net/MEET/2018epigenetics/xiaohua.html
孙前文(清华大学)
http://i.bio360.net/MEET/2018epigenetics/qianwen.html
王泽峰(中科院上海生命科学研究院)
http://i.bio360.net/MEET/2018epigenetics/zefeng.html
http://i.bio360.net/MEET/2018epigenetics/hsueh.html
http://i.bio360.net/MEET/2018epigenetics/yutaka.html
韩为东 (301 医院)
http://i.bio360.net/MEET/2018epigenetics/weidong.html
http://i.bio360.net/MEET/2018epigenetics/jungkyoon.html
http://i.bio360.net/MEET/2018epigenetics/xinyu.html
罗成 (中科院上海药物研究所)
http://i.bio360.net/MEET/2018epigenetics/chengluo.html
李国红(中科院生物物理所)
http://i.bio360.net/MEET/2018epigenetics/guohong.html
颉伟 (清华大学)
http://i.bio360.net/MEET/2018epigenetics/weixie.html
Yijun Ruan(Jackon Lab)
http://i.bio360.net/MEET/2018epigenetics/yijun.html
http://i.bio360.net/MEET/2018epigenetics/zhongshen.html
Chandrima Das(India )
http://i.bio360.net/MEET/2018epigenetics/chandrima.html
http://i.bio360.net/MEET/2018epigenetics/lijung.html
汤富酬(北京大学)
http://i.bio360.net/MEET/2018epigenetics/fuchou.html
邓宏魁(北京大学)
http://i.bio360.net/MEET/2018epigenetics/hongkui.html
大会日程:
19th, Sept, 2018 | ||
8:30-8:40 | Opening | |
I.Chemical and Biological Perspectives of DNA Modifications | ||
8:40-9:05 | A vitamin C-derived DNA modification | Guoliang Xu |
9:05-9:25 | Dynamic regulation of DNA methylation | Bing Zhu |
9:25-9:50 | Active DNA Demethylation by Vertebrate DNA Methyltransferases | James Shen |
9:50-10:15 | Chemical-assisted Sequencing of Epigenetic Nucleic Acid Modifications | Chengqi Yi |
10:15-10:40 | Break+Group Photograph | |
Chair of the second half part : Fei Lan(FuDan University) | ||
10:40-11:05 | Single-cell multi-omic analysis of human organs | Kun Zhang |
11:05-11:30 | Structural Insight into dynamic regulation of DNA methylation | Yanhui Xu |
11:30-11:40 | Epigenome Reprogramming as a Basis for Combination Therapy | Naoko Hattori |
11:40-11:50 | Short Talk 2 | |
11:50-13:00 | Lunch | |
13:00-14:30 | Poster session I | |
II.Chemical and Biological Perspectives of histone modifications | ||
14:30-14:55 | Structure and Function of YEATS Domain in Health and Disease | Haitao Li |
14:55-15:20 | The Dynamic Regulation of Histone Methylation | Fei Lan |
15:20-15:45 | De-acetylation and Epigenomic regulation | Ullas Kolthur-Seetharam (Tata Institute, India) |
15:45-16:10 | Metabolic regulation of gene expression | Zhimin Lu |
16:10-16:30 | Tea Break | |
Chair of the second half part: Lijung Juan(Academia Sinica, Taipei) | ||
16:30-16:55 | Epgenetics and Adipogenesis: Implications of Histone modifications Languages | Tapas K. Kundu |
16:55-17:20 | Crosstalk between histone modifications during heterochromatin assembly | Jun-ichi Nakayama |
20th, Sept, 2018 | ||
III. Chemical and epigenetic regulation of transcription | ||
8:30-8:55 | R-loopsin physiology and pathology | Xiangdong Fu |
8:55-9:20 | Epigenetic Regulation of Hematopoietic Stem Cell Development | Feng Liu |
9:20-9:50 | The Diversity and Function of Long Noncoding RNAs | Lingling Chen |
9:50-10:15 | Cis-acting lncRNAs in transcription and chromatin regulation | Xiaohua Shen |
10:15-10:40 | Tea Break | |
Chair of the second half part: Hongkui Deng(Peking University) | ||
10:40-11:05 | R-loop, the general chromatin feature in Arabidopsis genomes | Qianwen Sun |
11:05-11:30 | Re-thinking the coding capacity of non-coding RNA | Zefeng Wang |
11:30-11:40 | A long noncoding RNA in telomere maintenance, gene regulation and inter-chromosomal pairing | Hsueh-Ping Chu |
11:40-11:50 | Short Talk 4 | |
11:50-13:00 | Lunch | |
13:00-14:30 | Poster session 2 | |
IV.Clinical Epigenetics | ||
14:30-14:55 | Implication of Long Non-coding RNAs in Cancer Biology | Yutaka Kondo |
14:55-15:20 | Enhanced anti-tumor activity of PD1 blockade by DNA demethylating agent in the clinic | Weidong Han |
15:20-15:45 | Talk 21 | Teh Bin Tean |
15:45-16:10 | Functional prediction of causal regulatory variants identifies a novel autism gene | Jung Kyoon Choi |
16:10-16:30 | Tea Break | |
Chair of the second half part: Zefeng Wang(Academia Sinica) | ||
16:30-16:55 | DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human Cancers | Xingyu Lu |
16:55-17:20 | Drug discovery of protein-protein interactions by targeting epi-modification state of untargetable protein | Cheng Luo |
21st, Sept, 2018 | ||
V.Chemical and biological perspectives of the higher-order chromatin structure | ||
8:30-8:55 | Talk 25 | Jun-ichi Nakayama |
8:55-9:20 | Dynamic regulation of higher-order chromatin structures in gene regulation | Guohong Li |
9:20-9:45 | Reprogramming of chromatin architecture in early mammalian development | Wei Xie |
9:45-10:10 | Combinatorial mechanisms in 3D genome folding and transcription regulation | Yijun Ruan |
10:10-10:30 | Tea Break | |
Chair of the second half part: Lingling Chen(Academia Sinica, Shanghai) | ||
10:30-10:55 | Systematic Mapping of RNA-Chromatin Interactions In Vivo | Sheng Zhong |
10:55-11:20 | Talk 30 | |
11:20-11:30 | Decoding the Epigenetic Landscape by the Histone Readers: Implications in human diseases | Chandrima Das |
11:30-11:40 | Short talk 6 | |
11:40-13:00 | Lunch | |
VI. Developmental Epigenetics | ||
13:00-13:25 | Talk 31 | |
13:25-13:50 | CROSSTALK OF N-A-ACETYLTRANSFERASE AND DNA METHYLATION IN DEVELOPMENT AND DISEASE | Li-Jung Juan |
13:50-14:15 | Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells | Fuchou Tang |
14:15-14:25 | Short talk 7 | |
14:25-14:35 | Short talk 8 | |
14:35-14:45 | Short talk 9 | |
14:45-14:55 | Short talk 10 | |
14:55-15:15 | Tea Break | |
Chair of the second half part: Xiangdong Fu(UCSD) | ||
15:40-15:50 | Short Talk 11 | |
15:50-16:00 | Short Talk 12 | |
16:00-16:25 | Talk35 | |
16:25-16:50 | Small Molecule-induced Cell Fate Reprogramming | Hongkui Deng |
16:50-17:00 | Closing |
欲实时把握表观遗传学理论、技术和应用的最新进展,请参加第四届发育和疾病的表观遗传学上海国际研讨会(2018 年 9 月 18-21 日,上海)点击“阅读原文”即可注册。
会务组
联系人: 张老师 闫老师
邮箱:chris.zhang@bio360.net / event@bio360.net /
电话:021-59555696 / 18516613552 / 18512189851