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第四届发育与疾病表观遗传学国际研讨会
2018-01-29 09:31:42 报名参加

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生物 360 邀您共享表观遗传学研究饕餮盛宴 “第四届发育和疾病的表观遗传学上海国际研讨会 2018 年 9 月 18-21 日,上海),点击注册:

http://i.bio360.net/MEET/2018epigenetics/sign.html

表观遗传学 (Epigenetics) 是论及决定细胞时代间基因组 转录记忆 的与 DNA 序列改变无关的信号, 介导者和机制的学科。表观遗传事件通过对 DNA 和组蛋白的 共价修饰 , 以转录的 RNA 和翻译的蛋白的方式, 调节和功能化地展示编码在 DNA 序列中遗传的结构信息, 继而产生在 时空多维空间 无限多样的表型。健康表观遗传稳态是确保高等生物发育过程中细胞分化和谱系化正常开展所依据的优态基因组表达的必要前提。基因组表观遗传信息界面的异常是包括肿瘤, 代谢类和神经系统疾病在内的疾患的病因, 病理学机制之一。

为了加大本次大会学术交流的力度, 除了 6 个主题 /36 个 25 分钟报告以外, 我们还安排了 12 个 10 分钟报告, 后者是从两个时长 1.5 小时的墙报摘要者中遴选出来的。欢迎各位与会者积极报名并提交墙报摘要!

会议主题:

主题 1. DNA 修饰的化学和生物学

主题 2. 组蛋白修饰的化学和生物学

主题 3. 转录的化学生物学和表观调控

主题 4. 临床表观遗传学

主题 5. 染色质高级结构的化学和生物学

主题 6. 发育的表观遗传学

演讲嘉宾:

徐国良(中科院上海生命科学研究院)

报告题目:A vitamin C-derived DNA modification

http://i.bio360.net/MEET/2018epigenetics/customer.html

朱冰 (中科院生物物理研究所)

报告题目:Dynamic regulation of DNA methylation

http://i.bio360.net/MEET/2018epigenetics/bingzhu.html

James Shen(Academia Sinica,Taipei)

报告题目:Active DNA Demethylation by VertebrateDNA Methyltransferases

http://i.bio360.net/MEET/2018epigenetics/james.html

伊成器(北京大学)

报告题目:Chemical-assisted Sequencing ofEpigenetic Nucleic Acid Modifications

http://i.bio360.net/MEET/2018epigenetics/chengqi.html

张鹍 UCSD)

报告题目:Single-cell multi-omic analysis of humanorgans.

http://i.bio360.net/MEET/2018epigenetics/kunzhang.html

徐彦辉(复旦大学)

报告题目:Structural Insight into dynamicregulation of DNA methylation

http://i.bio360.net/MEET/2018epigenetics/yanhui.html

Naoko Hattori(Japan)

报告题目:Epigenome Reprogramming as a Basis for Combination Therapy

http://i.bio360.net/MEET/2018epigenetics/naoko.html

刘峰 (中科院动物所)

报告题目:EpigeneticRegulation of Hematopoietic Stem Cell Development

http://i.bio360.net/MEET/2018epigenetics/fengliu.html

陈玲玲 (中科院上海生命科学研究院)

报告题目:THE DIVERSITY AND FUNCTION OF LONG NONCODING RNAS

http://i.bio360.net/MEET/2018epigenetics/lingling.html

沈晓骅 (清华大学)

报告题目:Cis-acting lncRNAs intranscription and chromatin regulation

http://i.bio360.net/MEET/2018epigenetics/xiaohua.html

孙前文(清华大学)

报告题目:R-loop, the general chromatin feature in Arabidopsis genomes

http://i.bio360.net/MEET/2018epigenetics/qianwen.html

王泽峰(中科院上海生命科学研究院)

报告题目:Re-thinking the codingcapacity of non-coding RNA.

http://i.bio360.net/MEET/2018epigenetics/zefeng.html

Hsueh-Ping Chu(National Taiwan University)

报告题目:A long noncoding RNA in telomere maintenance,gene regulation and inter-chromosomal pairing.

http://i.bio360.net/MEET/2018epigenetics/hsueh.html

Yutaka Kondo(Japan)

报告题目:Implication of Long Non-coding RNAs in CancerBiology

http://i.bio360.net/MEET/2018epigenetics/yutaka.html

韩为东 301 医院)

报告题目:Enhanced anti-tumoractivity of PD1 blockade by DNA demethylating agent in the clinic

http://i.bio360.net/MEET/2018epigenetics/weidong.html

JungKyoon Choi(Singapore)

报告题目:Functional prediction of causal regulatory variants identifies a novelautism gene

http://i.bio360.net/MEET/2018epigenetics/jungkyoon.html

陆星宇(上海)

报告题目:DNA 5-Hydroxymethylcytosines from Cell-freeCirculating DNA as Diagnostic Biomarkers for Human Cancers

http://i.bio360.net/MEET/2018epigenetics/xinyu.html

罗成 (中科院上海药物研究所)

报告题目:Drugdiscovery of protein-protein interactions by targeting epi-modification site ofuntargetable protein

http://i.bio360.net/MEET/2018epigenetics/chengluo.html

李国红(中科院生物物理所)

报告题目:Dynamic regulation ofhigher-order chromatin structures in gene regulation

http://i.bio360.net/MEET/2018epigenetics/guohong.html

颉伟 (清华大学)

报告题目:Reprogramming ofchromatin architecture in early mammalian development

http://i.bio360.net/MEET/2018epigenetics/weixie.html

Yijun Ruan(Jackon Lab)

报告题目:Combinatorial mechanisms in3D genome folding and transcription regulation

http://i.bio360.net/MEET/2018epigenetics/yijun.html

Sheng Zhong(UCSD)

报告题目:Systematic Mapping of RNA-ChromatinInteractions In Vivo

http://i.bio360.net/MEET/2018epigenetics/zhongshen.html

Chandrima Das(India )

报告题目:Decoding the EpigeneticLandscape by the Histone Readers: Implications in human diseases

http://i.bio360.net/MEET/2018epigenetics/chandrima.html

Li-Jung Juan(Academia Sinica,Taipei)

报告题目:CROSSTALK OF N-A-ACETYLTRANSFERASE AND DNAMETHYLATION IN DEVELOPMENT AND DISEASE

http://i.bio360.net/MEET/2018epigenetics/lijung.html

汤富酬(北京大学)

报告题目:Single-cellmulti-omics sequencing of mouse early embryos and embryonic stem cells

http://i.bio360.net/MEET/2018epigenetics/fuchou.html

邓宏魁(北京大学)

报告题目:SmallMolecule-induced Cell Fate Reprogramming

http://i.bio360.net/MEET/2018epigenetics/hongkui.html


大会日程:

19th, Sept, 2018

8:30-8:40

Opening


I.Chemical and Biological Perspectives of DNA Modifications
Chair of the first half part:  Kazu Ushijima (Tokyo)

8:40-9:05

A vitamin C-derived DNA modification

Guoliang Xu
(Academia Sinica, Shanghai)

9:05-9:25

Dynamic regulation of DNA methylation

Bing Zhu
(Academia Sinica, Beijing)

9:25-9:50

Active DNA Demethylation by Vertebrate DNA Methyltransferases

James Shen
(Academia Sinica, Taipei)

9:50-10:15

Chemical-assisted Sequencing of Epigenetic Nucleic Acid Modifications

Chengqi Yi
( Peking University)

10:15-10:40

Break+Group Photograph



Chair of the second half part : Fei Lan(FuDan University)

10:40-11:05

Single-cell multi-omic analysis of human organs

Kun Zhang
(UCSD)

11:05-11:30

Structural Insight into dynamic regulation of DNA methylation

Yanhui Xu 
( Fudan University)

11:30-11:40

Epigenome Reprogramming as a Basis for Combination Therapy

Naoko Hattori
(Tokyo,Japan)

11:40-11:50

Short Talk 2


11:50-13:00

Lunch


13:00-14:30

Poster session I



II.Chemical and Biological Perspectives of histone modifications
Chair of the first half part : Youngjun Kim(Korea, Seul)

14:30-14:55

Structure and Function of YEATS Domain in Health and Disease

Haitao Li
(Tsinghua University),

14:55-15:20

The Dynamic Regulation of Histone Methylation

Fei Lan
(Fudan University)

15:20-15:45

 De-acetylation and Epigenomic regulation

 Ullas Kolthur-Seetharam

(Tata Institute, India)

15:45-16:10

Metabolic regulation of gene expression

Zhimin Lu
(MD Anderson)

16:10-16:30

Tea Break



Chair of the second half part: Lijung Juan(Academia Sinica, Taipei)

16:30-16:55

Epgenetics and Adipogenesis: Implications of Histone modifications Languages

Tapas K. Kundu
(India)

16:55-17:20

Crosstalk between histone modifications  during heterochromatin assembly

Jun-ichi Nakayama
(Japan)

 

20th, Sept, 2018


III. Chemical and epigenetic regulation of transcription
Chair of the first half part: Shyam PRABHAKAR (Singapore)

8:30-8:55

R-loopsin physiology and pathology

Xiangdong Fu
(UCSD)

8:55-9:20

Epigenetic Regulation of Hematopoietic Stem Cell Development

Feng Liu
(Academia Sinica, Beijing)

9:20-9:50

The Diversity and Function of Long Noncoding RNAs

Lingling Chen
(Academia Sinica,Shanghai)

9:50-10:15

Cis-acting lncRNAs in transcription and chromatin regulation

Xiaohua Shen
(Tsinghua University)

10:15-10:40

Tea Break



Chair of the second half part: Hongkui Deng(Peking University)

10:40-11:05

R-loop, the general chromatin feature in Arabidopsis genomes

Qianwen Sun
(Tsinghua University)

11:05-11:30

Re-thinking the coding capacity of non-coding RNA

Zefeng Wang
( Academia Sinica,Shanghai)

11:30-11:40

A long noncoding RNA in telomere maintenance, gene regulation and inter-chromosomal pairing

Hsueh-Ping Chu 
(National Taiwan University)

11:40-11:50

Short Talk 4


11:50-13:00

Lunch


13:00-14:30

Poster session 2



IV.Clinical Epigenetics
Chair of the first half part : Tapas Kundu(India)

14:30-14:55

Implication of Long Non-coding RNAs in Cancer Biology

Yutaka Kondo
(Nagoya University, Japan)

14:55-15:20

Enhanced anti-tumor activity of PD1 blockade by DNA demethylating agent in the clinic

Weidong Han
(301 Hospital, Beijing);

15:20-15:45

Talk 21

Teh Bin Tean
(Cancer Center, Singapore),

15:45-16:10

Functional prediction of causal regulatory variants identifies a novel autism gene

Jung Kyoon Choi
(Korea)

16:10-16:30

Tea Break



Chair of the second half part: Zefeng Wang(Academia Sinica)

16:30-16:55

DNA 5-Hydroxymethylcytosines from Cell-free Circulating DNA as Diagnostic Biomarkers for Human Cancers

Xingyu Lu
(Shanghai)

16:55-17:20

Drug discovery of protein-protein interactions by targeting epi-modification state of untargetable protein

Cheng Luo
(Academia Sinica,Shanghai)

21st, Sept, 2018


V.Chemical and biological perspectives of the higher-order chromatin structure
Chair of the first half part: Young-Joon Kim( Korea)

8:30-8:55

Talk 25

Jun-ichi Nakayama
(Tokyo,Japan)

8:55-9:20

Dynamic regulation of higher-order chromatin structures in gene regulation

Guohong Li
(Adademia Sinica, Beijing)

9:20-9:45

Reprogramming of chromatin architecture in early mammalian development

Wei Xie
(Tsinghua University)

9:45-10:10

Combinatorial mechanisms in 3D genome folding and transcription regulation

Yijun Ruan
(Jackson Lab, USA)

10:10-10:30

Tea Break



Chair of the second half part: Lingling Chen(Academia Sinica, Shanghai)

10:30-10:55

Systematic Mapping of RNA-Chromatin Interactions In Vivo

Sheng Zhong
(UCSD)

10:55-11:20

Talk 30


11:20-11:30

Decoding the Epigenetic Landscape by the Histone Readers: Implications in human diseases

Chandrima Das

11:30-11:40

Short talk 6


11:40-13:00

Lunch



VI. Developmental Epigenetics
Chair of the first half part: Guoliang Xu(Academia Sinica, Shanghai)

13:00-13:25

Talk 31


13:25-13:50

CROSSTALK OF N-A-ACETYLTRANSFERASE AND DNA METHYLATION IN DEVELOPMENT AND DISEASE

Li-Jung Juan
(Adademia Sinica,Taipei)

13:50-14:15

Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells

Fuchou Tang
(Peking University)

14:15-14:25

Short talk 7


14:25-14:35

Short talk 8


14:35-14:45

Short talk 9


14:45-14:55

Short talk 10


14:55-15:15

Tea Break



Chair of the second half part: Xiangdong Fu(UCSD)

15:40-15:50

Short Talk 11


15:50-16:00

Short Talk 12


16:00-16:25

Talk35


16:25-16:50

Small Molecule-induced Cell Fate Reprogramming

Hongkui Deng
(Peking University)

16:50-17:00

Closing


 

欲实时把握表观遗传学理论、技术和应用的最新进展,请参加第四届发育和疾病的表观遗传学上海国际研讨会(2018 年 9 月 18-21 日,上海)点击“阅读原文”即可注册。

会务组

联系人: 张老师 闫老师

邮箱:chris.zhang@bio360.net / event@bio360.net /

电话:021-59555696 / 18516613552 / 18512189851